Hydroxyl/t-Butyl protected carboxyl PEG reagent, Hydroxy-PEG1-CH₂CO₂tBu, Purity 95%

Synonym: 287174-32-7; Tert-butyl 2-(2-hydroxyethoxy)acetate; Hydroxy-PEG1-CH₂CO₂tBu; Hydroxy-PEG1-CH₂-Boc; HO-PEG1-CH₂COOtBu

MDL: MFCD27635155
CAS Number: 287174-32-7
PubChem CID: 57802514

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG1-CH₂CO₂tBu is a PEG linker featuring a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG1 spacer enhances hydrophilicity and solubility in aqueous media. The hydroxyl group serves as a versatile site for chemical modifications, while the t-butyl ester provides acid-labile protection, allowing controlled activation of the carboxyl group.

Molecular Weight

176.2

Molecular Formula

C₈H₁₆O₄

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl protected carboxyl

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

95%

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG1-CH₂CO₂tBu is used in research to develop functionalized compounds, hydrophilic linkers, and bioconjugation strategies. The hydroxyl group supports the introduction of additional functional groups, and the t-butyl ester facilitates precise carboxyl deprotection, making it suitable for applications in material synthesis and molecular interaction studies.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

Hydroxyl/t-Butyl protected carboxyl PEG reagent, Hydroxy-PEG1-CH2CO2tBu, Purity 95%

Hydroxyl/t-Butyl protected carboxyl PEG reagent, Hydroxy-PEG1-CH₂CO₂tBu, Purity 95%