Hydroxyl/t-Butyl protected carboxyl PEG reagent, Hydroxy-PEG5-CH₂CO₂tBu, Purity 95%

Synonym: 1807530-05-7; Hydroxy-PEG5-CH₂CO₂tBu; Hydroxy-PEG5-t-Butyl acetate; Hydroxy-PEG4-O-Boc; HO-PEG5-CH₂COOtBu

MDL: MFCD27977509
CAS Number: 1807530-05-7
PubChem CID: 77078247

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG5-CH₂CO₂tBu is a PEG linker composed of a terminal hydroxyl group and a t-butyl-protected carboxyl group. The PEG5 spacer enhances water solubility and hydrophilicity, while the hydroxyl group provides a versatile site for chemical modifications. The t-butyl group offers acid-labile protection, allowing precise carboxyl group activation under controlled conditions.

Molecular Weight

352.4

Molecular Formula

C₁₆H₃₂O₈

Functional Group 1

Hydroxyl

Functional Group 2

t-Butyl protected carboxyl

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

95%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG5-CH₂CO₂tBu is utilized in research for the synthesis of functionalized molecules and the study of biomolecular interactions. The hydroxyl group facilitates modifications for experimental purposes, and the t-butyl-protected carboxyl group is used in controlled deprotection studies, making it suitable for developing linkers and model compounds in research and development projects.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

Hydroxyl/t-Butyl protected carboxyl PEG reagent, Hydroxy-PEG5-CH2CO2tBu, Purity 95%

Hydroxyl/t-Butyl protected carboxyl PEG reagent, Hydroxy-PEG5-CH₂CO₂tBu, Purity 95%