Hydroxyl/TBDMS PEG reagent, TBDMS-PEG5, Purity 98%

Synonym: 134179-40-1; TBDMS-PEG4-OH; 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol; TBDMS-PEG4-alcohol; TBDMS-PEG5

CAS Number: 134179-40-1
PubChem CID: 14827669

Size

1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TBDMS-PEG5 is a PEG linker with a TBDMS (tert-butyldimethylsilyl) alcohol protecting group and a terminal hydroxyl group. The TBDMS group offers stability during synthesis and can be selectively removed using acetyl chloride. The PEG5 chain enhances solubility and hydrophilicity in aqueous environments.

Molecular Weight

308.5

Molecular Formula

C₁₄H₃₂O₅Si

Functional Group 1

Hydroxyl

Functional Group 2

TBDMS

Reactive Group 1

Acetyl chloride

Reactive Group 2

Nucleophile

Form

Oil

Purity

98%

Identity

Confirmed by NMR.

Applications

TBDMS-PEG5 is used in bioconjugation, drug delivery, and polymer synthesis. Its terminal hydroxyl group supports further functionalization, while the removable TBDMS group provides controlled reactivity, making it ideal for constructing hydrophilic linkers and functionalized biomaterials.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.