Hydroxyl/THP PEG reagent, THP-PEG5, Purity 98%

Synonym: 128660-97-9; THP-PEG5; THP-PEG4-OH; 2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol; MFCD26127805

MDL: MFCD26127805
CAS Number: 128660-97-9
PubChem CID: 10731287

Size

1 g; 5 g; 10 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

THP-PEG5 is a PEG linker featuring a tetrahydropyranyl (THP) protecting group and a terminal hydroxyl group. The THP group provides acid-labile protection for alcohol functionalities, while the hydrophilic PEG5 spacer enhances solubility in aqueous media. The terminal hydroxyl group offers a reactive site for further chemical modifications.

Molecular Weight

278.3

Molecular Formula

C₁₃H₂₆O₆

Functional Group 1

Hydroxyl

Functional Group 2

THP

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

THP-PEG5 is used in organic synthesis, drug delivery, and bioconjugation. The THP group allows for controlled deprotection under acidic conditions, while the terminal hydroxyl enables versatile functionalization, making it ideal for developing hydrophilic conjugates and complex molecular structures in pharmaceutical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.