Cat. No.: X24-03-YW0632
Hydroxyl/THP PEG reagent, THP-PEG5, Purity 98%
Synonym: 128660-97-9; THP-PEG5; THP-PEG4-OH; 2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol; MFCD26127805
- MDL: MFCD26127805
- CAS Number: 128660-97-9
- PubChem CID: 10731287
Properties
Description
THP-PEG5 is a PEG linker featuring a tetrahydropyranyl (THP) protecting group and a terminal hydroxyl group. The THP group provides acid-labile protection for alcohol functionalities, while the hydrophilic PEG5 spacer enhances solubility in aqueous media. The terminal hydroxyl group offers a reactive site for further chemical modifications.
Molecular Formula
C13H26O6
Functional Group 1
Hydroxyl
Reactive Group 2
Nucleophile
Identity
Confirmed by NMR.
Applications
THP-PEG5 is used in organic synthesis, drug delivery, and bioconjugation. The THP group allows for controlled deprotection under acidic conditions, while the terminal hydroxyl enables versatile functionalization, making it ideal for developing hydrophilic conjugates and complex molecular structures in pharmaceutical research.
For Research Use Only. Not For
Clinical Use.