Iodoacetamide/t-Butyl ester PEG reagent, Iodoacetamido-PEG8-t-butyl ester, Purity 96%

Synonym: Iodoacetamido-PEG8-t-butyl ester; BP-22102; Tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-[(2-iodoacetyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

PubChem CID: 77078245

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Iodoacetamido-PEG8-t-butyl ester is a bifunctional PEG reagent featuring an iodoacetamide group and a t-butyl ester-protected carboxyl group. The iodoacetamide acts as a potent alkylating agent, capable of forming stable covalent bonds with thiol groups, while the t-butyl ester provides temporary protection that can be removed under acidic conditions.

Molecular Weight

665.6

Molecular Formula

C₂₅H₄₈INO₁₁

Functional Group 1

Iodoacetamide

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Solid

Purity

96%

Identity

Confirmed by NMR.

Applications

Iodoacetamido-PEG8-t-butyl ester is used in protein modification, bioconjugation, and drug delivery. It enables selective thiol labeling for cysteine residues, while the acid-labile t-butyl ester facilitates controlled deprotection, making it ideal for targeted synthesis and creating stable, functional conjugates in biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.