Maleimide/t-Butyl ester PEG reagent, Methylamino-PEG1-t-butyl ester, Purity 98%

Synonym: 1807521-03-4; Methylamino-PEG1-Boc; Tert-BUTYL 3-[2-(METHYLAMINO)ETHOXY]PROPANOATE; Tert-butyl 3-(2-(methylamino)ethoxy)propanoate

CAS Number: 1807521-03-4
PubChem CID: 86291513

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Methylamino-PEG1-t-butyl ester is a PEG linker featuring a methylamine group and a t-butyl-protected ester. The methylamine group reacts efficiently with carboxylic acids, carbonyls (ketones, aldehydes), and other electrophilic groups. The t-butyl ester offers acid-labile protection, enabling controlled release of the carboxylic acid functionality. The PEG1 spacer enhances water solubility and hydrophilicity.

Molecular Weight

203.3

Molecular Formula

C₁₀H₂₁NO₃

Functional Group 1

Maleimide

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Liquid

Purity

98%

Solubility

Water, DCM

Identity

Confirmed by NMR.

Applications

Methylamino-PEG1-t-butyl ester is used in research for designing functionalized linkers, exploring acid-mediated deprotection mechanisms, and studying molecular interactions. Its dual-functional groups allow versatile chemical modifications, making it suitable for synthesizing hydrophilic materials, bioconjugates, and advanced molecular scaffolds.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.