Maleimide/t-Butyl ester PEG reagent, Methylamino-PEG2-t-butyl ester, Purity 98%

Synonym: 1807521-04-5; Methylamino-PEG2-t-butyl ester; Methylamino-PEG2-Boc; Tert-butyl 3-(2-(2-(methylamino)ethoxy)ethoxy)propanoate

MDL: MFCD28155207
CAS Number: 1807521-04-5
PubChem CID: 86291523

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Methylamino-PEG2-t-butyl ester is a PEG linker with a methylamino group and a t-butyl-protected ester. The methylamine group allows for efficient reactivity with carboxylic acids and carbonyl compounds, while the t-butyl ester provides acid-labile protection for controlled carboxylic acid activation. The PEG2 spacer enhances water solubility and hydrophilicity.

Molecular Weight

247.3

Molecular Formula

C₁₂H₂₅NO₄

Functional Group 1

Maleimide

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Methylamino-PEG2-t-butyl ester is used in research to develop functionalized molecules, explore amine-reactive conjugations, and study acid-mediated deprotection mechanisms. Its dual-functional groups enable versatile applications in linker design, biomolecular modifications, and the synthesis of hydrophilic materials for experimental studies.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.