Maleimide/t-Butyl ester PEG reagent, Methylamino-PEG4-t-butyl ester, Purity 98%

Synonym: 1621616-14-5; Methylamino-PEG4-Boc; Tert-BUTYL 5,8,11,14-TETRAOXA-2-AZAHEPTADECAN-17-OATE; Methylamino-PEG5-t-butyl ester

MDL: MFCD28155210
CAS Number: 1621616-14-5
PubChem CID: 86291526

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Methylamino-PEG4-t-butyl ester is a PEG linker featuring a methylamine group and a t-butyl-protected ester. The methylamine group reacts with carboxylic acids, carbonyls (ketones, aldehydes), and other electrophilic groups. The t-butyl ester offers acid-labile protection, enabling controlled activation of the carboxylic acid. The PEG4 spacer enhances solubility and hydrophilicity in aqueous environments.

Molecular Weight

335.4

Molecular Formula

C₁₆H₃₃NO₆

Functional Group 1

Maleimide

Functional Group 2

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Methylamino-PEG4-t-butyl ester is widely used in research for synthesizing functionalized linkers, exploring acid-deprotection reactions, and studying molecular interactions. Its dual-functional groups allow versatile chemical modifications, making it suitable for designing hydrophilic biomaterials, bioconjugates, and advanced molecular scaffolds in experimental applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.