Maleimide/NHS ester PEG reagent, 6-Maleimido-hexanoic NHS ester, Purity 98%

Synonym: 55750-63-5; N-Succinimidyl 6-Maleimidohexanoate; 6-Maleimidohexanoic acid N-hydroxysuccinimide ester; EMCS

MDL: MFCD00043043
CAS Number: 55750-63-5
PubChem CID: 5091655

Size

250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

6-Maleimido-hexanoic NHS ester is a linker molecule containing a maleimide group and an NHS ester. The NHS ester is highly reactive with primary amines, enabling the labeling of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group reacts with thiol groups to form stable covalent bonds, facilitating the attachment of biomolecules to thiol-containing compounds. This linker provides a hydrophilic spacer to enhance solubility in aqueous media.

Molecular Weight

308.3

Molecular Formula

C₁₄H₁₆N₂O₆

Functional Group 1

Maleimide

Functional Group 2

NHS ester

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

6-Maleimido-hexanoic NHS ester is utilized in research for bioconjugation, protein labeling, and surface functionalization. Its dual-reactive groups make it ideal for crosslinking biomolecules, modifying surfaces with thiol groups, and facilitating the creation of stable, covalently linked complexes in experimental studies.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.