Cat. No.: X24-03-YW0762
Maleimide/NHS ester PEG reagent, 6-Maleimido-hexanoic NHS ester, Purity 98%
Synonym: 55750-63-5; N-Succinimidyl 6-Maleimidohexanoate; 6-Maleimidohexanoic acid N-hydroxysuccinimide ester; EMCS
- MDL: MFCD00043043
- CAS Number: 55750-63-5
- PubChem CID: 5091655
Properties
Description
6-Maleimido-hexanoic NHS ester is a linker molecule containing a maleimide group and an NHS ester. The NHS ester is highly reactive with primary amines, enabling the labeling of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group reacts with thiol groups to form stable covalent bonds, facilitating the attachment of biomolecules to thiol-containing compounds. This linker provides a hydrophilic spacer to enhance solubility in aqueous media.
Molecular Formula
C14H16N2O6
Functional Group 1
Maleimide
Functional Group 2
NHS ester
Identity
Confirmed by NMR.
Applications
6-Maleimido-hexanoic NHS ester is utilized in research for bioconjugation, protein labeling, and surface functionalization. Its dual-reactive groups make it ideal for crosslinking biomolecules, modifying surfaces with thiol groups, and facilitating the creation of stable, covalently linked complexes in experimental studies.
For Research Use Only. Not For
Clinical Use.