Maleimide/NHS ester PEG reagent, Mal-amido-PEG24-NHS, Purity 95%

Synonym: 2226733-37-3; Mal-amido-PEG24-NHS; MAL-dPEG(R)24-NHS ester

MDL: MFCD11041160
CAS Number: 2226733-37-3
PubChem CID: 89408683

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-amido-PEG24-NHS is a PEG linker containing a maleimide group and an NHS ester. The maleimide group allows for conjugation with thiol-containing biomolecules, forming a stable covalent bond. The NHS ester reacts with primary amines, such as those on proteins and amine-modified oligonucleotides, enabling further functionalization. The long hydrophilic PEG spacer (24 units) enhances solubility in aqueous environments, making this compound ideal for applications requiring enhanced water solubility and bioconjugation efficiency.

Molecular Weight

1,394.6

Molecular Formula

C₆₂H₁₁₁N₃O₃₁

Functional Group 1

Maleimide

Functional Group 2

NHS ester

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

Mal-amido-PEG24-NHS is commonly used in research for protein labeling, oligonucleotide conjugation, and the development of bioconjugates, such as antibody-drug conjugates (ADCs). It enables stable attachment to thiol and amine-containing molecules, allowing for the creation of customized biomolecular tools and drug delivery systems.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.