Maleimide/NHS PEG reagent, Mal-PEG6-NHS ester, Purity 98%

Synonym: 1599472-25-9; Mal-PEG6-NHS ester; Mal-PEG6-NHS; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate; 4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester

CAS Number: 1599472-25-9
PubChem CID: 60146184

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-PEG6-NHS ester functions as a PEG linker characterized by both maleimide and NHS esters within its structure. Its hydrophilic PEG spacer increases solubility when dissolved in aqueous media, allowing the NHS ester to label primary amines t-from proteins or similar compounds containing amino functionalities.

Molecular Weight

530.5

Molecular Formula

C₂₃H₃₄N₂O₁₂

Functional Group 1

Maleimide

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid or viscous liquid

Purity

98%

Solubility

DCM, DMSO, DMF

Identity

Confirmed by NMR.

Applications

Mal-PEG6-NHS ester is particularly useful in targeted drug delivery and bioconjugation strategies. The maleimide group allows for specific conjugation with thiol-containing molecules, such as proteins or peptides. It can be used to attach drugs or imaging agents to targeted biomolecules, enabling precise delivery or detection.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.