Description
PCL(2k)-PEG(2k)-MAL is a self-assembling block copolymer with polycaprolactone (PCL) as hydrophobic segment and PEG as hydrophilic block. The maleimide group reacts with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Applications
PCL(2k)-PEG(2k)-MAL can be used to prepare nanoparticles or micelles for the encapsulation and delivery of substances. Among them, PCLs provide hydrophobic cores for encapsulating hydrophobic substances.