Maleimide/PNP PEG reagent, Mal-amido-PEG2-Val-Cit-PAB-PNP, Purity 98%

Synonym: 2112738-13-1; Mal-amido-PEG2-Val-Cit-PAB-PNP; EX-A5857; MFCD30828687; AKOS040742063

MDL: MFCD30828687
CAS Number: 2112738-13-1
PubChem CID: 129009582

Size

50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-amido-PEG2-Val-Cit-PAB-PNP is a reagent grade cleavable ADC linker containing a maleimide group that reacts with thiol-containing molecules. The Val-Cit linker is cleaved specifically by Cathepsin B, and PNP can be substituted by nucleophiles.

Molecular Weight

854.9

Molecular Formula

C₃₉H₅₀N₈O₁₄

Functional Group 1

Maleimide

Functional Group 2

PNP

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Mal-amido-PEG2-Val-Cit-PAB-PNP is used in targeted drug delivery and bioconjugation research, facilitating controlled payload release within cells due to Cathepsin B cleavage and enabling efficient thiol conjugation.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.