Maleimide/TFP PEG reagent, Mal-amido-PEG8-TFP ester, Purity 95%

Synonym: 1924596-31-5; (2,3,5,6-Tetrafluorophenyl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate; 2,3,5,6-tetrafluorophenyl 1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate; mal-dPEG(8)-TFP

MDL: MFCD28505514
CAS Number: 1924596-31-5
PubChem CID: 91757745

Size

250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-amido-PEG8-TFP ester is a PEG linker featuring a maleimide group and a TFP ester. The maleimide group enables thiol-specific reactions under pH conditions between 6.5 and 7.5, forming stable covalent bonds. The TFP ester reacts efficiently with primary amines and is more hydrolysis-resistant compared to NHS esters. The PEG8 spacer enhances solubility and hydrophilicity in aqueous media.

Molecular Weight

740.7

Molecular Formula

C₃₂H₄₄F₄N₂O₁₃

Functional Group 1

Maleimide

Functional Group 2

TFP

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Liquid

Purity

95%

Identity

Confirmed by NMR.

Applications

Mal-amido-PEG8-TFP ester is utilized in research for bioconjugation, protein labeling, and synthesizing multifunctional biomolecules. Its dual-reactive groups enable precise thiol and amine modifications, making it suitable for creating hydrophilic linkers, exploring molecular interactions, and designing functional materials in experimental applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.