Description
Mal-PEG4-trimethylammonium chloride is a PEG linker featuring a maleimide group and a quaternary ammonium moiety. The maleimide group selectively reacts with thiol groups to form stable covalent bonds, while the trimethylammonium group imparts a permanent positive charge. The PEG4 spacer enhances hydrophilicity and solubility in aqueous media.
Applications
Mal-PEG4-trimethylammonium chloride is used in research for thiol-specific bioconjugation, creating cationic functionalized biomolecules, and developing charged surfaces. Its dual functionality is valuable in synthesizing charged hydrophilic linkers, exploring protein modification, and constructing advanced molecular scaffolds for experimental applications.