NHS PEG reagent, m-PEG25-NHS ester, Purity 97%

Synonym: mPEG24-CH₂CH₂COONHS ester; mPEG24-OCH₂CH₂COONHS ester; mPEG24-OCH₂CH₂COONHS ester

CAS Number: 174569-25-6
PubChem CID: 51340984

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

m-PEG25-NHS ester acts as another PEG linker characterized by its inclusion of an NHS ester moiety, which allows it to label primary amines t-located within proteins or other related substances containing amino functionalities like modified oligonucleotides. Additionally, the hydrophilic nature of its PEG spacer increases solubility in aqueous environments, making it useful for various applications during research.

Molecular Weight

1258.5

Molecular Formula

C₅₆H₁₀₇NO₂₉

Functional Group 1

Ester

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Form

Solid or viscous liquid

Purity

97%

Identity

Confirmed by NMR.

Applications

In drug delivery, it can be used to PEGylate drugs or nanoparticles, increasing their circulation time and reducing clearance by the immune system. The long PEG chain provides enhanced stealth properties. It can also be used in the modification of biomolecules, such as antibodies and enzymes, to improve their stability and solubility.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.