NHS PEG reagent, m-PEG8-succinimidyl carbonate, Purity 98%

Synonym: 1372860-04-2; m-PEG8-succinimidyl carbonate; M-PEG8-SUCCINIMIDYLCARBONATE; (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl carbonate

CAS Number: 1372860-04-2
PubChem CID: 129012723

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

m-PEG8-succinimidyl carbonate serves as a PEG linker characterized by its succinimidyl carbonate group, which acts as an effective leaving group commonly reacting with nucleophilic amines. This compound is commonly used in bioconjugation reactions for the modification and functionalization of biomolecules. It can be employed in the development of drug delivery systems, immunoassays, and protein labeling techniques.

Molecular Weight

525.6

Molecular Formula

C₂₂H₃₉NO₁₃

Functional Group 1

NHS

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Solid or viscous liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

This reagent is commonly employed for the selective modification of biomolecules. The succinimidyl carbonate group reacts with nucleophiles, such as amines on proteins or peptides, leading to the development of bioconjugates. This compound is particularly useful in creating stable linkages for biopharmaceutical applications, including vaccine formulation and antibody-drug conjugates.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.