NHS/Maleimide PEG reagent, N-(NHS ester-PEG3)-N-bis(PEG3-Mal)

Synonym: NHS-PEG3-bis(PEG3-Mal); PEG3-NHS-PEG3-Mal; N-(PEG3-NHS)-N-bis(PEG3-maleimide); N-bis(PEG3-Maleimide)-N-(NHS-PEG3)

Size

25 mg; 50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(NHS ester-PEG3)-N-bis(PEG3-Mal) contains NHS ester-PEG3 and bis(PEG3-Mal) groups. The NHS ester enables conjugation with amine groups, and the Mal (maleimide) groups can react with thiol groups. The PEG chains increase solubility and provide flexibility. It is often used in the design of bioconjugates, especially for targeted drug delivery and protein modification. The multiple reactive groups offer possibilities for complex conjugation strategies.

Molecular Weight

999

Molecular Formula

C₄₄H₆₆N₆O₂₀

Functional Group 1

NHS

Functional Group 2

Ester

Functional Group 3

Maleimide

Reactive Group 1

Thiol

Reactive Group 2

Amine

Form

Solid or viscous liquid

Identity

Confirmed by NMR.

Applications

This compound is utilized in crosslinking applications, particularly for creating linkages between biomolecules by maleimide-thiol chemistry. It’s beneficial in forming stable conjugates for therapeutic or diagnostic purposes, as well as in creating multifunctional constructs for targeted delivery.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.