NHS/Maleimide PEG reagent, Mal-PEG5-NHS ester, Purity 98%

Synonym: 1807537-42-3; Mal-PEG5-NHS ester; Mal-PEG5-NHS; MAL-PEG5-NHSESTER; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate

CAS Number: 1807537-42-3
PubChem CID: 77078334

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-PEG5-NHS ester acts as a PEG linker characterized by both maleimide and NHS ester functionalities. Its hydrophilic PEG spacer improves solubility when dissolved in water-based environments. The NHS ester allows for labeling primary amines t-found within proteins or other similar compounds containing amino groups, while the maleimide component reacts with thiol groups to form covalent bonds that enable connections between biomolecules with thiols.

Molecular Weight

486.5

Molecular Formula

C₂₁H₃₀N₂O₁₁

Functional Group 1

NHS

Functional Group 2

Ester

Functional Group 3

Maleimide

Reactive Group 1

Thiol

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Mal-PEG5-NHS ester is often utilized in the conjugation of biomolecules for targeted drug delivery or as a linker in various biotechnological applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.