OPSS/Alcohol PEG reagent, (2-pyridyldithio)-PEG4-alcohol, Purity ≥95%

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Cat. No.: X26-09-ZQ396

OPSS/Alcohol PEG reagent, (2-pyridyldithio)-PEG4-alcohol, Purity ≥95%

Synonym: (2-Pyridyldithio)-PEG4-hydroxyl; Pyridyldithio-PEG4-alcohol; (2-Pyridyldithio)-polyethylene glycol4-alcohol; 2-Pyridyldithio-tetraethylene glycol-alcohol

CAS Number: 851961-99-4
PubChem CID: 86049505

OPSS/Alcohol PEG reagent, (2-pyridyldithio)-PEG4-alcohol, Purity ≥95%

Size

100 mg; 250 mg

Price

Datasheet

MSDS

Properties

Description

This heterobifunctional reagent pairs a 2-pyridyldithio group with a primary alcohol terminal via a tetraethylene glycol (PEG4) spacer. The 2-pyridyldithio group undergoes selective thiol-disulfide exchange with free sulfhydryl groups. The alcohol terminal provides a site for esterification, carbamylation, or conversion to leaving groups. The PEG4 spacer maintains water compatibility.

Molecular Weight

319.4

Molecular Formula

C₁₃H₂₁NO₄S₂

Functional Group 1

OPSS

Functional Group 2

Alcohol

Reactive Group 1

Thiol

Reactive Group 2

Carboxylic acid

Reactive Group 3

Acid chloride

Purity

≥95%

Solubility

The compound is soluble in DMSO, DCM, and DMF.

Applications

This product can be used for thiol-selective conjugation, attaching hydroxylated handles to thiolated carbohydrates, and developing cleavable probe constructs.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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