PFP PEG reagent, Endo-BCN-PEG2-PFP ester, Purity 95%

Synonym: 1421932-53-7; Endo-BCN-PEG2-PFP ester; Perfluorophenyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate; Prfluorophenyl 1-(bicyclo[6.1.0]non-4-Yn-9-Yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-Oate; 4,7,12-Trioxa-10-azatridecanoic acid, 13-bicyclo[6.1.0]non-4-yn-9-yl-11-oxo-, 2,3,4,5,6-pentafluorophenyl ester

CAS Number: 1421932-53-7
PubChem CID: 77078462

Size

50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Endo-BCN-PEG2-PFP ester is a click chemistry active ester. PFP esters, more stable than NHS esters in aqueous solution, are used to label primary amines (-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group enables reaction with azide-tagged biomolecules.

Molecular Weight

519.5

Molecular Formula

C₂₄H₂₆F₅NO₆

Functional Group 1

PFP

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Azide

Form

Liquid

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Endo-BCN-PEG2-PFP ester is crucial in bioconjugation, facilitating specific labeling of primary amines in biomolecules. Its stability in aqueous environments ensures reliable conjugation reactions. The BCN group broadens its utility, allowing for efficient coupling reactions with azide-tagged biomolecules, making it valuable in protein labeling, drug delivery, and biomaterials development.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.