Description
N-(propanoic acid)-N-bis(m-PEG12) is a monodisperse PEG reagent featuring a terminal carboxylic acid group and two PEG chains. This compound serves as a versatile linker for conjugating with primary amine-containing molecules in the presence of coupling agents such as EDC or HATU. The symmetric structure of the PEG chains ensures uniformity and reproducibility in conjugation reactions, facilitating the formation of stable amide bonds.
Applications
N-(propanoic acid)-N-bis(m-PEG12) can be used in bioconjugation chemistry and drug delivery systems. Its bifunctional nature allows for the selective attachment of the terminal carboxylic acid group to primary amines on biomolecules, proteins, peptides, or small molecules. This controlled conjugation process enables the creation of well-defined PEGylated constructs with enhanced solubility, stability, and biocompatibility.