Description
t-Boc-aminooxy-PEG5-propargyl is a reagent grade click crosslinker, designed for copper-catalyzed azide-alkyne click chemistry reactions. The terminal carboxylic acids react with primary amino groups in the presence of activators (EDC, HATU, etc) to form a stable amide bond. The hydrophilic PEG spacer increases water solubility.
Applications
t-Boc-aminooxy-PEG5-propargyl is used in molecular biology and bioconjugation research, facilitating efficient copper-catalyzed click chemistry reactions with azide compounds or biomolecules to form a stable triazole linkage, making it ideal for modifying biomolecules.