SIA Crosslinker

Synonym: 39028-27-8; N-Succinimidyl Iodoacetate; SIA Crosslinker; Iodoacetic acid N-hydroxysuccinimide ester; 2,5-Dioxopyrrolidin-1-yl 2-iodoacetate

CAS Number: 39028-27-8
PubChem CID: 3299230

Size

500 mg; 1 g; 2 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SIA crosslinker is designed to form covalent bonds between biomolecules, enabling the study of protein-protein interactions and the stabilization of protein complexes. It finds applications in various research fields, including the development of therapeutic agents and the understanding of cellular processes.

Molecular Weight

283

Molecular Formula

C₆H_6INO₄

Functional Group 1

Ester

Functional Group 2

Thiol

Functional Group 3

None

Reactive Group 1

Alkenyl

Reactive Group 2

Alkynyl

Form

Solid

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

SIA crosslinkers are employed in protein crosslinking studies to form stable covalent bonds between proteins. This can help in understanding protein-protein interactions, structural studies, and improving the stability of therapeutic proteins.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.