SPDP/Azide PEG reagent, SPDP-PEG11-azide, Purity ≥95%

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Cat. No.: X26-09-ZQ371

SPDP/Azide PEG reagent, SPDP-PEG11-azide, Purity ≥95%

Synonym: SPDP-PEG11-N₃; SPDP-polyethylene glycol11-azide; 3-(2-Pyridyldithio)propionate-PEG11-azide; SPDP-undecaethylene glycol-azide

SPDP/Azide PEG reagent, SPDP-PEG11-azide, Purity ≥95%

Size

100 mg; 250 mg; 500 mg

Price

Datasheet

MSDS

Properties

Description

This dual bioorthogonal linker couples a pyridyldithio (SPDP) handle to a terminal azide group via an undecaethylene glycol (PEG11) spacer. The SPDP group enables exchange with free thiol groups to generate reversible disulfide linkages. The azide group participates in copper-catalyzed or copper-free click chemistry with alkynes. The long PEG11 chain ensures superior water solubility.

Molecular Weight

768

Molecular Formula

C₃₂H₅₇N₅O₁₂S₂

Functional Group 1

SPDP

Functional Group 2

Azide

Reactive Group 1

Thiol

Reactive Group 2

Alkyne

Reactive Group 3

BCN

Purity

≥95%

Solubility

The compound is soluble in DMSO, DCM, and DMF.

Applications

This product can be used for dual click and thiol crosslinking, functionalizing thiolated glycans with azide handles, and modular bioconjugation.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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