SPDP/Carboxylic acid PEG reagent, SPDP-PEG4-acid, Purity ≥95%

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Cat. No.: X26-09-ZQ409

SPDP/Carboxylic acid PEG reagent, SPDP-PEG4-acid, Purity ≥95%

Synonym: SPDP-PEG4-carboxylic acid; SPDP-polyethylene glycol4-acid; 3-(2-Pyridyldithio)propionate-PEG4-acid; SPDP-tetraethylene glycol-acid; SPDP-PEG4-carboxyl

CAS Number: 581065-97-6
PubChem CID: 51341021

SPDP/Carboxylic acid PEG reagent, SPDP-PEG4-acid, Purity ≥95%

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

This product is a heterobifunctional polyethylene glycol (PEG) crosslinker possessing a pyridyldithiol (SPDP) group and a carboxyl group. The SPDP motif is highly reactive toward free thiols to form reducible disulfide linkages, releasing 2-pyridinethione as a measurable byproduct. The carboxylic acid terminus can be coupled to primary amine-containing molecules via standard amide formation.

Molecular Weight

462.6

Molecular Formula

C₁₉H₃₀N₂O₇S₂

Functional Group 1

SPDP

Functional Group 2

Carboxylic acid

Reactive Group 1

Thiol

Reactive Group 2

Amine

Reactive Group 3

Alcohol

Purity

≥95%

Applications

This product can be used for constructing reversible biomolecular conjugates, designing smart materials with reduction-triggered cleavage, and functionalizing solid surfaces in organic chemistry and chemical biology research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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