SPDP/Carboxylic acid PEG reagent, SPDP-PEG8-acid, Purity ≥95%

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Cat. No.: X26-09-ZQ397

SPDP/Carboxylic acid PEG reagent, SPDP-PEG8-acid, Purity ≥95%

Synonym: SPDP-PEG8-carboxylic acid; SPDP-polyethylene glycol8-acid; 3-(2-Pyridyldithio)propionate-PEG8-acid; SPDP-octaethylene glycol-acid

CAS Number: 1334177-96-6
PubChem CID: 51341023

SPDP/Carboxylic acid PEG reagent, SPDP-PEG8-acid, Purity ≥95%

Size

100 mg; 500 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

This heterobifunctional crosslinker links a pyridyldithio (SPDP) group to a terminal carboxylic acid through an octaethylene glycol (PEG8) spacer. The SPDP handle reacts specifically with free sulfhydryl groups to form reversible disulfide links. The carboxylic acid terminal undergoes amidation with primary amines. The PEG8 spacer provides high aqueous solubility.

Molecular Weight

638.8

Molecular Formula

C₂₇H₄₆N₂O₁₁S₂

Functional Group 1

SPDP

Functional Group 2

Carboxylic acid

Reactive Group 1

Thiol

Reactive Group 2

Amine

Reactive Group 3

Alcohol

Purity

≥95%

Applications

This product can be used for thiol-to-amine crosslinking of oligosaccharides, building cleavable bioconjugate probes, and functionalizing biomaterial surfaces.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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