SPDP/NHS ester PEG reagent, SPDP-PEG-24-NHS ester, Purity ≥95%

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Inquiry

Cat. No.: X26-09-ZQ323

SPDP/NHS ester PEG reagent, SPDP-PEG-24-NHS ester, Purity ≥95%

Synonym: SPDP-PEG24-NHS ester; SPDP-polyethylene glycol24-NHS ester; 3-(2-Pyridyldithio)propionate-PEG24-NHS ester; SPDP-PEG24-succinimidyl ester

SPDP/NHS ester PEG reagent, SPDP-PEG-24-NHS ester, Purity ≥95%

Size

100 mg; 500 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

This long-chain heterobifunctional crosslinker connects a pyridyldithio (SPDP) handle to an N-hydroxysuccinimide (NHS) ester via a polyethylene glycol (PEG24) chain. The SPDP moiety reacts with free thiols to form reversible disulfide bonds. The NHS ester targets primary amines for stable amide bond formation. The long PEG24 spacer significantly increases solubility and reduces spatial crowding.

Molecular Weight

1439.7

Molecular Formula

C₆₄H₁₁₄N₂O₂₉S₂

Functional Group 1

SPDP

Functional Group 2

NHS ester

Reactive Group 1

Thiol

Reactive Group 2

Amine

Purity

≥95%

Applications

This product can be used for thiol-to-amine crosslinking on large polysaccharides, constructing water-soluble bioconjugates, and surface modification.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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