SPDP/NHS ester PEG reagent, SPDP-PEG12-NHS ester, Purity ≥95%

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Inquiry

Cat. No.: X26-09-ZQ373

SPDP/NHS ester PEG reagent, SPDP-PEG12-NHS ester, Purity ≥95%

Synonym: SPDP-PEG12-NHS; SPDP-polyethylene glycol12-NHS ester; SPDP-PEG12-succinimidyl ester; 3-(2-Pyridyldithio)propionate-PEG12-NHS ester

CAS Number: 2601437-72-1
PubChem CID: 51341026

SPDP/NHS ester PEG reagent, SPDP-PEG12-NHS ester, Purity ≥95%

Size

100 mg; 500 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

This heterobifunctional crosslinker links a pyridyldithio (SPDP) handle to an N-hydroxysuccinimide (NHS) ester through a dodecaethylene glycol (PEG12) chain. The SPDP group reacts specifically with free thiols to form reversible disulfide bonds. The NHS ester targets primary amines for amide bond formation. The long PEG12 chain delivers exceptional water solubility.

Molecular Weight

912.1

Molecular Formula

C₃₉H₆₅N₃O₁₇S₂

Functional Group 1

SPDP

Functional Group 2

NHS ester

Reactive Group 1

Thiol

Reactive Group 2

Amine

Purity

≥95%

Applications

This product can be used for thiol-to-amine crosslinking of large polysaccharides, constructing water-soluble probe conjugates, and surface functionalization.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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