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SPDP/NHS ester PEG reagent, SPDP-PEG6-NHS ester, Purity ≥95%
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Amino PEG
Amino-PEG10-acid (Cat#: X24-03-YW0001) N-(Mal-PEG6)-N-bis(PEG3-amine) (Cat#: X24-03-YW0002) Amino-PEG23-amine (Cat#: X24-03-YW0056) Amino-PEG20-t-butyl ester (Cat#: X24-03-YW0057) Amino-PEG1-amine (Cat#: X24-03-YW0058) Gly-PEG3-amine TFA salt (Cat#: X24-03-YW0064) Amino-PEG9-amine (Cat#: X24-03-YW0068) Amino-PEG8-amine (Cat#: X24-03-YW0072) Amino-PEG8-t-butyl ester (Cat#: X24-03-YW0087)
Biotin PEG
Biotin-PEG2-azide (Cat#: X24-03-YW0091) Biotin-PEG5-azide (Cat#: X24-03-YW0113) Biotin-PEG6-t-butyl ester (Cat#: X24-03-YW0114) Dde biotin azide plus (Cat#: X24-03-YW0115) Biotin-PEG2-NH-Boc (Cat#: X24-03-YW0116) Biotin-PEG11-amine (Cat#: X24-03-YW0117) Biotin-PEG4-amide (Cat#: X24-03-YW0118) Biotin-PEG4-azide (Cat#: X24-03-YW0119) Biotin-PEG12-NHS ester (Cat#: X24-03-YW0124)
DBCO PEG
DBCO-PEG5-TFP ester (Cat#: X24-03-YW0294) DBCO-C3-alcohol (Cat#: X24-03-YW0306) Hydroxy-PEG7-DBCO (Cat#: X24-03-YW0307) DBCO-C5-acid (Cat#: X24-03-YW0308) DBCO-PEG2-amine (Cat#: X24-03-YW0310) DBCO STP ester (Cat#: X24-03-YW0311) DBCO-PEG6-DBCO (Cat#: X24-03-YW0312)
Poly PEG
m-PEG-succinic acid (Cat#: X24-10-WXX03) Lipoamide-PEG-Mal (Cat#: X24-10-WXX05) m-PEG-SPDP (Cat#: X24-10-WXX06) Lipoamide-PEG-biotin (Cat#: X24-10-WXX07) Rhodamine-PEG-Mal (Cat#: X24-10-WXX08) Cholesterol-PEG-methoxy (Cat#: X24-10-WXX10) DSPE-PEG-Ald (Cat#: X24-10-WXX12) 4-Arm PEG-OH (Cat#: X24-10-WXX13)
PEG Acid
m-PEG4-(CH2)3-acid (Cat#: X24-09-YYX001) m-PEG9-acid (Cat#: X24-09-YYX005) m-PEG1-acid (Cat#: X24-09-YYX008) Biotin-PEG2-acid (Cat#: X24-09-YYX011) Acid-PEG4-t-butyl ester (Cat#: X24-09-YYX015) Amino-PEG3-acid (Cat#: X24-09-YYX018) m-PEG11-CH2CO2H (Cat#: X24-09-YYX020) Amino-PEG4-CH2CO2H (Cat#: X24-09-YYX022)
PEG Azide
t-boc-N-amido-PEG5-azide (Cat#: X24-09-YYX148) Aminooxy-PEG4-azide (Cat#: X24-09-YYX246) AZD-PEG2-azide (Cat#: X24-09-YYX248) Azido-PEG12-azide (Cat#: X24-09-YYX249) Trityl-PEG10-azide (Cat#: X24-09-YYX250) Bromoacetamido-PEG2-azide (Cat#: X24-09-YYX251) Azido-PEG24-alcohol (Cat#: X24-09-YYX255) m-PEG6-azide (Cat#: X24-09-YYX257)
Bromo PEG
Bromo-PEG2-methyl ester (Cat#: X24-03-YW0205) Bromoacetamido-PEG8-acid (Cat#: X24-03-YW0209) Bromoacetamido-PEG3-acid (Cat#: X24-03-YW0213) Amino-PEG8-Bromo (Cat#: X24-03-YW0215) Bis-bromoacetamido-PEG11 (Cat#: X24-03-YW0216) Bromoacetamido-PEG8-t-butyl ester (Cat#: X24-03-YW0218) Bromo-PEG1-CH2CO2-t-Bu (Cat#: X24-03-YW0220)


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Cat. No.: X26-09-ZQ387

SPDP/NHS ester PEG reagent, SPDP-PEG6-NHS ester, Purity ≥95%

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Synonym: SPDP-PEG6-NHS; SPDP-polyethylene glycol6-NHS ester; SPDP-PEG6-succinimidyl ester; 3-(2-Pyridyldithio)propionate-PEG6-NHS ester

  • CAS Number: 1818294-32-4
  • PubChem CID: 77078426
SPDP/NHS ester PEG reagent, SPDP-PEG6-NHS ester, Purity ≥95%
Size
100 mg; 250 mg; 500 mg
Price
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Datasheet
Datasheet
MSDS
MSDS
Properties
Description
This heterobifunctional crosslinker pairs a pyridyldithio (SPDP) group with an N-hydroxysuccinimide (NHS) ester via a hexaethylene glycol (PEG6) chain. The SPDP handle enables thiol-disulfide exchange with free sulfhydryl groups. The NHS ester targets primary amines for covalent attachment. The PEG6 spacer provides balanced solubility and physical distance.
Molecular Weight
647.8
Molecular Formula
C27H41N3O11S2
Functional Group 1
SPDP
Functional Group 2
NHS ester
Reactive Group 1
Thiol
Reactive Group 2
Amine
Purity
≥95%
Solubility
The compound is soluble in DCM.
Applications
This product can be used for thiol-to-amine crosslinking on glycans, constructing cleavable bioconjugate probes, and functionalizing biomaterial surfaces.
Storage
Store at -20°C.
For Research Use Only. Not For Clinical Use.
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