Sulfo DBCO/TFP PEG reagent, Sulfo DBCO-TFP ester, Purity 95%

Synonym: 2268816-76-6; Sulfo DBCO-TFP ester; HY-151789; CS-0620034

CAS Number: 2268816-76-6
PubChem CID: 164577360

Size

10 mg; 25 mg; 100 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Sulfo DBCO-TFP ester is a water-soluble labeling reagent designed for efficient incorporation of the Sulfo DBCO moiety onto amine-containing molecules. Featuring an amine-reactive TFP ester group, this reagent facilitates straightforward and effective bioconjugation reactions. The presence of a hydrophilic, sulfonated spacer arm significantly enhances the water solubility of DBCO-modified molecules, often rendering them completely soluble in aqueous media. Additionally, the short spacer arm minimally affects the mass of the modified molecules, preserving their structural integrity and functionality.

Molecular Weight

604.5

Molecular Formula

C₂₈H₂₀F₄N₂O₇S

Functional Group 1

Sulfo DBCO

Functional Group 2

TFP

Functional Group 3

None

Form

Reported

Purity

95%

Solubility

DMSO, DMF, DCM, THF, Chloroform, Water

Identity

Confirmed by NMR.

Applications

Sulfo DBCO-TFP ester is widely utilized in bioconjugation applications, particularly for labeling and functionalizing amine-containing biomolecules such as proteins, peptides, and antibodies. Its water solubility and efficient reactivity make it ideal for preparing conjugates for various biochemical assays, imaging studies, and therapeutic applications.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.