Sulfo-NHS

Synonym: 106627-54-7; N-Hydroxysulfosuccinimide sodium salt; Sulfo-NHS; sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate; n-hydroxysulfosuccinimide sodium

CAS Number: 106627-54-7
PubChem CID: 3520574

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Sulfo-NHS is a water-soluble reagent that is frequently used to activate carboxyl groups for conjugation reactions. It is widely applied in biochemistry and biotechnology for modifying proteins and other biomolecules, especially when working in aqueous environments.

Molecular Weight

217.1

Molecular Formula

C₄H₄NN_aO₆S

Functional Group 1

Hydroxyl

Functional Group 2

NHS

Functional Group 3

Sulfonyl

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid

Identity

Confirmed by NMR.

Applications

Sulfo-NHS is primarily used for coupling reactions in bioconjugation. It enhances the reactivity of carboxylic acids with amines to form stable amide bonds, making it useful in the labeling of proteins and peptides for various biochemical applications, including the development of biopharmaceuticals.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.