Cat. No.: X24-10-WXX331
Sulfone/t-Butyl ester PEG reagent, m-PEG3-sulfone-PEG3-t-butyl ester, Purity 96%
Synonym: 2055041-00-2; m-PEG3-sulfone-PEG3-Boc; m-PEG3-Sulfone-PEG3-t-butyl ester; M-PEG3-SULFONE-PEG3-T-BUTYLESTER; DTXSID701124951
- CAS Number: 2055041-00-2
- PubChem CID: 119058262
Size
100 mg; 250 mg; 500 mg; 1 g
Properties
Description
m-PEG3-sulfone-PEG3-t-butyl ester is a reagent grade PEG linker with sulfone and t-butyl ester moieties. Under acidic conditions, the t-butyl is removed. The sulfone reacts with thiol groups of proteins. The PEG spacer increases water solubility.
Molecular Formula
C20H40O10S
Functional Group 1
Sulfone
Functional Group 2
t-Butyl ester
Reactive Group 3
Carbonyl
Identity
Confirmed by NMR.
Applications
m-PEG3-sulfone-PEG3-t-butyl ester is a linker in medicinal chemistry that facilitates the conjugation of small molecules to biomolecules while maintaining a balance of hydrophilicity and hydrophobicity that aids in cellular uptake.
For Research Use Only. Not For
Clinical Use.