Cat. No.: X24-03-YW0250
TBDMS PEG reagent, Tris (O-TBDMS)3, Purity 96%
Synonym: 102522-47-4; 2-(Tert-Butyl-dimethyl-silanyloxy)-1,1-bis-(Tert-butyl-dimethyl-silanyloxymethyl)-ethylamine; 6-(((Tert-Butyldimethylsilyl)oxy)methyl)-2,2,3,3,9,9,10,10-octamethyl-4,8-dioxa-3,9-disilaundecan-6-amine; 1,3-Bis[[Tert-butyl(dimethyl)silyl]oxy]-2-[[Tert-butyl(dimethyl)silyl]oxymethyl]propan-2-amine
- MDL: MFCD22574795
- CAS Number: 102522-47-4
- PubChem CID: 15299066
Properties
Description
Tris(O-TBDMS)3 is a tris-functional linker featuring three tert-butyldimethylsilyl (TBDMS) protecting groups. The TBDMS moiety serves as an acid-labile protecting group, providing temporary shielding for reactive functional groups during synthesis or chemical transformations. This tri-functional linker offers versatility in organic synthesis and enables precise control over the deprotection of TBDMS groups under mild acidic conditions.
Molecular Formula
C22H53NO3Si3
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
Tris(O-TBDMS)3 finds wide utility in organic synthesis, particularly in the protection and deprotection of hydroxyl or amino groups in complex molecules. The TBDMS protecting groups can be selectively removed using mild acidic conditions, allowing for the controlled release of functional groups at specific stages of synthesis. This linker facilitates the synthesis of intricate organic compounds, including pharmaceutical intermediates, natural products, and advanced materials, where precise manipulation of functional groups is essential for successful synthesis and downstream applications.
For Research Use Only. Not For
Clinical Use.
