Description
THP-PEG9 is a PEG linker featuring a tetrahydropyranyl (THP) protecting group and a hydrophilic PEG9 chain. The THP group provides acid-labile protection for alcohol functionalities, allowing controlled deprotection under mild acidic conditions. The PEG9 spacer enhances solubility and stability in aqueous environments.
Applications
THP-PEG9 is used in organic synthesis, drug delivery, and bioconjugation. Its THP group enables temporary protection of alcohol groups during multi-step reactions, while the hydrophilic PEG chain supports water-soluble conjugates, making it ideal for developing functionalized biomaterials and hydrophilic linkers.