THP/Hydroxyl PEG reagent, THP-PEG12, Purity 98%

Synonym: 92417-25-9; THP-PEG11-OH; 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(Oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; AKOS040743992

CAS Number: 92417-25-9
PubChem CID: 118796266

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

THP-PEG12 is a PEG linker featuring a tetrahydropyranyl (THP) group and a hydrophilic PEG12 spacer. The THP group serves as an acid-labile protecting group for alcohols, enabling controlled deprotection under acidic conditions. The PEG12 chain provides enhanced solubility and hydrophilicity in aqueous media.

Molecular Weight

586.7

Molecular Formula

C₂₇H₅₄O₁₃

Functional Group 1

THP

Functional Group 2

Hydroxyl

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

THP-PEG12 is employed in research for synthesizing functionalized molecules and studying controlled deprotection reactions. The THP group is useful for protecting alcohols during multi-step synthesis, while the PEG12 spacer supports solubility in aqueous systems, making it ideal for linker design and material development in research settings.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.