THP/Hydroxyl PEG reagent, THP-PEG4, Purity 95%

Synonym: 60221-37-6; THP-PEG3-OH; 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol; 2-{2-[2-(Oxan-2-yloxy)ethoxy]ethoxy}ethan-1-ol

CAS Number: 60221-37-6
PubChem CID: 13699403

Size

1 g; 5 g; 10 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

THP-PEG4 is a PEG linker featuring a tetrahydropyranyl (THP) protecting group and a terminal hydroxyl group. The THP group serves as an acid-labile protecting group for alcohols, allowing controlled deprotection under acidic conditions. The PEG4 chain enhances solubility and stability in aqueous environments, making it versatile for chemical and biomedical research.

Molecular Weight

234.3

Molecular Formula

C₁₁H₂₂O₅

Functional Group 1

THP

Functional Group 2

Hydroxyl

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

95%

Identity

Confirmed by NMR.

Applications

THP-PEG4 is used in research for designing hydrophilic linkers, protecting alcohol functionalities during multi-step synthesis, and studying deprotection mechanisms. Its hydroxyl group allows for further functionalization, and the THP group ensures temporary protection, making it ideal for creating functionalized materials and exploring synthetic strategies.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.