THP/Tosyl PEG reagent, THP-PEG7-Tos, Purity 98%

Synonym: THP-PEG7-Tos; 17-(Oxan-2-yloxy)-3,6,9,12,15-pentaoxaheptadecan-1-yl 4-methylbenzene-1-sulfonate; SCHEMBL15436972; QGSBMQZFPAVLBB-UHFFFAOYSA-N; AKOS040742735

PubChem CID: 86709891

Size

500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

THP-PEG7-Tos is a PEG linker featuring a tetrahydropyranyl (THP) protecting group and a tosyl (Tos) moiety. The THP group provides acid-labile protection for alcohol functionalities, while the tosyl group acts as an excellent leaving group for nucleophilic substitution reactions. The PEG7 chain enhances solubility and hydrophilicity in aqueous environments.

Molecular Weight

520.6

Molecular Formula

C₂₄H₄₀O₁₀S

Functional Group 1

THP

Functional Group 2

Tosyl

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

THP-PEG7-Tos is utilized in organic synthesis, bioconjugation, and drug development. The THP group enables controlled alcohol deprotection, while the tosyl group supports nucleophilic substitution, making it ideal for constructing hydrophilic linkers and advanced materials in pharmaceutical and biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.