Tosyl/t-Butyl ester PEG reagent, Tos-PEG4-t-butyl ester, Purity 98%

Synonym: Tos-PEG4-t-butyl ester; 217817-01-1; Tos-PEG4-t-butyl ester (Tos-PEG4-Boc); tert-butyl 3-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)propanoate; 3-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid tert-butyl ester

CAS Number: 217817-01-1
PubChem CID: 60146205

Size

1 g; 2g; 5 g; 10 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tos-PEG4-t-butyl ester is a reagent grade PEG linker with a tosyl group and a t-butyl ester. The mesyl group is used for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl-protected carboxyl group is deprotected.

Molecular Weight

432.5

Molecular Formula

C₂₀H₃₂O₈S

Functional Group 1

Tosyl

Functional Group 2

t-Butyl ester

Functional Group 3

None

Reactive Group 1

Nucleophile

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Tos-PEG4-t-butyl ester promotes drug conjugation while providing solubility advantages and potential stability of reaction intermediates, making it valuable in peptide- or protein-based drug delivery systems.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.