Properties
Description
Tos-PEG2-CH2CO2tBu is a reagent grade PEG linker with a tosyl group and a t-butyl ester. The PEG spacer increases water solubility. Under acidic conditions, the t-butyl-protected carboxyl group is deprotected. The tosyl group is used for nucleophilic substitution reactions.
Molecular Formula
C15H22O6S
Functional Group 2
t-Butyl protected carboxyl
Reactive Group 1
Nucleophile
Identity
Confirmed by NMR.
Applications
Tos-PEG2-CH2CO2tBu is often utilized in drug delivery systems due to its ability to enhance solubility and stability while providing sites for further modification, such as attaching therapeutic agents or targeting moieties.