Properties
Description
Tos-PEG3-CH2CO2tBu is a reagent grade PEG linker with a tosyl group and a t-butyl ester. The PEG spacer increases water solubility. Under acidic conditions, the t-butyl-protected carboxyl group is deprotected. The tosyl group is used for nucleophilic substitution reactions.
Molecular Formula
C17H26O7S
Functional Group 2
t-Butyl protected carboxyl
Reactive Group 1
Nucleophile
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
Tos-PEG3-CH2CO2tBu has applications in the solubilization and stabilization of drug candidates. It is also a useful tool for molecular biology, biomolecule interactions, and other applications.