Cat. No.: X24-10-WXX398
Tosyl/t-Butyl-protected carboxyl PEG reagent, Tos-PEG5-CH2CO2tBu, Purity 98%
Synonym: Tos-PEG5-CH2CO2tBu; 169751-73-9; Tos-PEG4-CH2-Boc; Tos-PEG5-CH2CO2t-butyl ester; Tos-PEG4-CH2COOtBu
- CAS Number: 169751-73-9
- PubChem CID: 77078235
Properties
Description
Tos-PEG5-CH2CO2tBu is a reagent grade PEG linker with a tosyl group and a t-butyl ester. The PEG spacer increases water solubility. The tosyl group is used for nucleophilic substitution reactions. Under acidic conditions, the t-butyl-protected carboxyl group is deprotected.
Molecular Formula
C21H34O9S
Functional Group 2
t-Butyl protected carboxyl
Reactive Group 1
Nucleophile
Identity
Confirmed by NMR.
Applications
Tos-PEG5-CH2CO2tBu is used in drug conjugation to improve the stability and solubility of active pharmaceutical ingredients (APIs). It is also a useful tool for molecular biology, biomolecule interactions, and other applications.
For Research Use Only. Not For
Clinical Use.