Cat. No.: X24-10-WXX426
Tosyl/t-Butyl-protected carboxyl PEG reagent, Tos-PEG6-CH2CO2tBu, Purity 98%
Synonym: Tos-PEG6-CH2CO2tBu; 1949793-62-7; Tos-PEG5-CH2COOtBu; (2-[2-(2-(2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy)-ethoxy)-ethoxy]-ethoxy)-acetic acid tert-butyl ester; {2-[2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-acetic acid tert-butyl ester
- CAS Number: 1949793-62-7
- PubChem CID: 121396727
Properties
Description
Tos-PEG6-CH2CO2tBu is a reagent grade PEG linker with a t-butyl ester and a tosyl group. The PEG spacer increases water solubility. Under acidic conditions, the t-butyl-protected carboxyl group is deprotected. The tosyl group is used for nucleophilic substitution reactions.
Molecular Formula
C23H38O10S
Functional Group 2
t-Butyl protected carboxyl
Reactive Group 1
Nucleophile
Identity
Confirmed by NMR.
Applications
Tos-PEG6-CH2CO2tBu is often utilized in drug delivery systems due to its ability to enhance solubility and stability while providing sites for further modification, such as attaching therapeutic agents or targeting moieties. It is also a useful tool for biomolecule interaction analysis and other applications.
For Research Use Only. Not For
Clinical Use.