TOTA PEG reagent, Boc-TOTA, Purity 95%

Synonym: 194920-62-2; Boc-TOTA; Tert-Butyl (3-(2-(2-(3-aminopropoxy)ethoxy)ethoxy)propyl)carbamate; N-Boc-4,7,10-trioxa-1,13-tridecanediamine; Tert-butyl N-[3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propyl]carbamate

CAS Number: 194920-62-2
PubChem CID: 11989604

Size

1 g; 5 g; 10 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Boc-TOTA is a versatile linker featuring an amino group with a Boc-protected amino moiety. The presence of the Boc protection enables controlled reactivity, which can be selectively activated under mild acidic conditions to unveil the free amine group.

Molecular Weight

320.4

Molecular Formula

C₁₅H₃₂N₂O₅

Functional Group 1

TOTA

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

Carbonyls

Reactive Group 3

NHS

Form

Reported

Purity

95%

Identity

Confirmed by NMR.

Applications

Boc-TOTA finds extensive application in peptide synthesis, solid-phase peptide coupling, and bioconjugation chemistry. Its controlled deprotection allows for precise manipulation of reactivity, making it suitable for the synthesis of complex peptide structures or the functionalization of biomolecules. Moreover, its compatibility with various coupling reagents and reaction conditions enables its use in diverse chemical transformations, offering tailored solutions for peptide modification, drug delivery systems, and materials science research.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.