SPDP/NHS ester PEG reagent, SPDP-PEG8-NHS ester, Purity ≥95%

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Inquiry

Cat. No.: X26-09-ZQ382

SPDP/NHS ester PEG reagent, SPDP-PEG8-NHS ester, Purity ≥95%

Synonym: SPDP-PEG8-NHS; SPDP-polyethylene glycol8-NHS ester; SPDP-PEG8-succinimidyl ester; 3-(2-Pyridyldithio)propionate-PEG8-NHS ester

CAS Number: 1252257-56-9
PubChem CID: 51341024

SPDP/NHS ester PEG reagent, SPDP-PEG8-NHS ester, Purity ≥95%

Size

100 mg; 500 mg; 1 g

Price

Datasheet

MSDS

Properties

Description

This amine-reactive crosslinker links a pyridyldithio (SPDP) group to an N-hydroxysuccinimide (NHS) ester through an octaethylene glycol (PEG8) spacer. The SPDP group undergoes exchange with free thiols to form reversible disulfide linkages. The NHS ester targets primary amines for stable amide formation. The PEG8 spacer provides high aqueous solubility.

Molecular Weight

735.9

Molecular Formula

C₃₁H₄₉N₃O₁₃S₂

Functional Group 1

SPDP

Functional Group 2

NHS ester

Reactive Group 1

Thiol

Reactive Group 2

Amine

Purity

≥95%

Applications

This product can be used for thiol-to-amine bioconjugation on oligosaccharides, modifying functional biomaterials, and preparing cleavable probe constructs.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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